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Hydrogels:CDDP@SulBC水凝膠

Hydrogels:CDDP@SulBC水凝膠

【Numbering】BKMB100016 【CAS】CAS
【Item No.】BKMB100016-2 【specification】
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Name: CDDP @ SulBC hydrogel
Composition: cisplatin, bacterial cellulose
Particle size: network
Application: regulating intestinal flora for precision chemoradiotherapy of intestinal cancer
Storage conditions: -4℃
Other instructions: the shelf life of half a year in the sealed state [Main advantages] When the hydrogel is placed in the reducing environment such as the intestinal tract, the disulfide bond is cracked into the sulfhydryl group, this reversible redox property is conducive to the construction of intestinal targeted drug release carrier. When the CDDP @ SulBC hydrogel is immersed in microenvironments such as artificial gastric juice (pH=1.4) and artificial intestinal fluid (pH=7.8), the electrostatic repulsion between the hydrogel of cellulose in alkaline environment releases the CDDP faster and more than in acidic environment.


Title:Regulation of gut microbiome with redox responsible bacterial cellulose

hydrogel for precision chemo-radiotherapy of intestinal cancer 


Article link:https://doi.org/10.1016/j.cej.2022.137340




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